If you would like further information about any of the studies below, pleaase email Jill Sutherland, SPCRN Database & Research Administrator.
| Study Title |
Chief Investigator |
Funder |
Recruitment |
The Scottish Family Health Study (Generation Scotland)
|
Professor Andrew Morris, University of Dundee |
Scottish Government Health Directorate |
East & West |
PATHWAY 1: Monotherapy vs Dual Therapy for Initial Treatment for Hypertension.
|
Professor Morris Brown, University of Cambridge |
BHF |
East, South East & West |
PATHWAY 2: Prevention and treatment of hypertension with algorithm based therapy (Pathway) Number 2. A multicentre Phase 4 study of optimal treatment of drug resistant hypertension.
|
Professor Morris Brown, University of Cambridge |
BHF |
East, South East & West |
PATHWAY 3: A multicentre phase 4 study of comparison of single and combination diuretics in low-rennin hypertension.
|
Professor Morris Brown, Univesity of Cambridge |
BHF |
East, South East & West |
Interstroke: Importance of conventional and emerging risk factors for stroke in different regions of the world and in different ethnic groups: a case controlled study.
|
Professor Peter Langhorne, University of Glasgow |
Chest Heart & Stroke Scotland
|
North East & West |
LEADER: Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results. A five year Multi-centre, International, Randomised Double-blind, Placebo-controlled Trial to Determine Liraglutide Effects on Cardiovascular Events (COMMERCIAL).
|
Professor Stephen Bain, University of Swansea |
Novo Nordisk
|
North East & West |
TECOS: A Randomized, Placebo Controlled Clinical Trial to Evaluate Cardiovascular Outcomes after Treatment with Sitagliptin in Patients with Type 2 Diabetes Mellitus and Inadequate Glycemic Control on Mono- or Dual Combination Oral Antihyperglycemic Therapy
(COMMERCIAL).
|
Professor Rury Holman, University of Oxford |
Merck & Co Inc
|
North East & West |
The impact of a telemetric monitoring service in type 2 Diabetes: randomised controlled trial with nested qualitative study.
|
Dr Brian McKinstry, University of Edinburgh |
Chief Scientist Office
|
North & South East |
SEARCH Breast Cancer - A Population based study of genetic predisposition and gene-environment interactions in breast cancer.
|
Dr Paul Pharoah, Cambridge |
Cancer Research UK
|
North, North East, West, South East & East |
SEARCH Endometrial Cancer - A Population based study of genetic predisposition and gene-environment interactions in endometrial cancer.
|
Dr Paul Pharoah, Cambridge |
Cancer Research UK
|
North, North East, West, South East & East |
SEARCH Other Cancers - A Population based study of genetic predisposition and gene-environment interactions in cancer.
|
Dr Paul Pharoah, Cambridge |
Cancer Research UK
|
North, North East, West, South East & East |
SEARCH Ovarian Cancer - A Population based study of genetic predisposition and gene-environment interactions in ovarian cancer.
|
Dr Paul Pharoah, Cambridge |
Cancer Research UK
|
North, North East, West, South East & East |
PAGES - Establishing a database to study gene-environment interactions and pharmacogenomics for asthma among Scottish children.
|
Dr Steve Turner, University of Aberdeen |
CSO
|
North & North East |
IQuAD Imrpoving the Quality of Dentistry: A randomised controlled trial comparing oral hygieve advice and peridontal instrumentation for the prevention and management of peridontal disease in dentate adults attending dental primary care.
|
Professor Jan Clarkson, Dental Health Services and Research Unit, Dundee |
HTA
|
North, North East, West, South East & East |
Maximising physical function in later life: a 2-centre randomised controlled trial of progressive resistance exercise training in combination with ACE inhibition.
|
Professor Marion McMurdo, University of Dundee |
CSO |
East |
TRACE RA: Trial of atorvastatin for the primary prevention of cardiovascular events in rheumatoid arthritis.
|
Professor George Kitas, Dudley Group of Hospitals NHS Trust |
Arthritis Research Campaign |
East |
GenCep: A pilot investigation into the feasibility of developing a record-linked database to study the genetics of childhood eczema in primary care
|
Prof Frank Sullivan, University of Dundee |
CSO |
East |
| 3P Study - Do phosphodiesterase 5 inhibitors improve exercise capacity in COPD patients with pulmonary hypertension?
|
Professor Allan Struthers, Ninewells Hospital, Dundee |
CSO |
East |
| The TASCFORCE Project: Tayside Screening for risk of cardiac events.
|
Professor Jill Belch, University of Dundee |
Chest Heart & Stroke Scotland |
East |
| BIOSTAT-Tayside CHF: A system BIOlogy Study to TAilored Treatment: Tayside Comprehensive Heart Funtion Study
|
Professor C C Lang, University of Dundee |
EC Seventhg Framework Programme (FP7) Co-operation-Health |
East |
| PROVIDE : Effect of nutritional supplementation on physical performance in elderly (COMMERCIAL)
|
Professor Marion McMurdo, University of Dundee |
Danone Research |
East |
| KIMVASC: Vitamin K to improve markers of vascular health and physical function in older patients with vascular disease - a randomised controlled trial
|
Dr Miles Witham, University of Dundee |
Chest Heart & Stroke Scotland |
East |
| DUAL/IDegLira: A trial comparing the efficacy and safety of insulin degludec/liraglutide, insulin degludec and liraglutide in subjects with type 2 diabetes (COMMERCIAL)
|
Ms Claire Henderson, Fife |
Novo Nordisk |
East |
| Identifying older heart failure patients with depression in primary care: a pilor study
|
Professor Marion McMurdo, University of Dundee |
CSO |
East |
| Exploring reasons for engagement with Hearty Lives Dundee.
|
Miss Ruth Dryden, SDHI, University of Dundee |
BHF |
East |
LANSCAPE-Comparison of a basal plus one insulin regimen (glargine/glulisine) with a biphasic insulin regimen (NovoMix 30) in type 2 patients after basal insulin optimisation
(COMMERCIAL).
|
Professor Jiten Vora, Royal Liverpool University Hospital
|
Sanofi Aventis
|
North East |
Epidemiology, prevalence and characteristics of heart failure with preserved left ventricular ejection fraction.
|
Prof Michael Frenneaux, School of Medicine and Dentistry, University of Aberdeen
|
BHF
|
North East |
WAIT - Parent-determined oral montelukast therapy for preschool wheeze
|
Prof Jonathon Grigg, Queen Mary Uni London/Barts and the London School of Medicine
|
NIHR/MRC Efficacy and Mechanism Evaluation programme
|
North East |
5 alpha Reductase Inhibitors and Metabolism Study (RIMS).
|
Professor Brian Walker, University of Edinburgh |
CSO
|
South East |
PROactive ( part 2). Physical Activity as a crucial Patient Reported Outcome in Chronic Obstructive Pulmonary Disease (COPD)
|
|
CSO
|
South East |
South Asian Carotid Plaques - A novel assessment of vascular disease, and its association with insulin resistance and adiposity in South Asians.
|
Professor Naveed Sattar, University of Glasgow |
CHSS
|
West |
Getting out of the House Study: A multi-centre randomised controlled trial of rehabilitation aimed at improving outdoor mobility for people who have had a stroke (TOMAS)
|
Dr Pip Logan, University of Nottingham |
HTA
|
West |
Patient/carer/clinician experience of palliative care in heart failure.
|
Professor Frances Mair, University of Glasgow |
BHF
|
West |
Developing a conceptual model of the burden of treatment and the work involved in living with heart failure.
|
Professor Frances Mair, University of Glasgow |
CSO
|
West |